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TargetRmtA
LigandBDBM50376154
Substrate/Competitorn/a
Meas. Tech.ChEMBL_475539 (CHEMBL925748)
IC50 14000±n/a nM
Citation Mai, ACheng, DBedford, MTValente, SNebbioso, APerrone, ABrosch, GSbardella, GDe Bellis, FMiceli, MAltucci, L epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. J Med Chem51:2279-90 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
RmtA
Name:RmtA
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39351.26
Organism:Emericella nidulans
Description:ChEMBL_475539
Residue:345
Sequence:
MSEIENSTITSSADRMVGMDHAEVRYFTSYDHHGIHEEMLKDDVRTRSYRDSIYQNRHIF
KDKVVLDVGCGTGILSMFAAKAGAKHVIGVDMSSIIEKAREIVAVNGLADKITLLQGKME
EVQLPFPSVDIIISEWMGYFLLYESMLDTVLYAQDRYLVPGGKIFPDKATMYLAGIEDGE
YKDDKIGFWDNVYGFDYSPMKEIALTEPLVDTVELKALVTDPCPIITFDLYTVTKEDLAF
EVPYSLPVKRSDFVHAVIAWFDIEFGACHKPINFSTGPHAKYTHWKQTVFYLRDVLTVEE
EESISGVLSNRPNDKNKRDLDINLTYKLETQDQTRFAEGGCFYRM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50376154
n/a
NameBDBM50376154
Synonyms:CHEMBL260149
TypeSmall organic molecule
Emp. Form.C20H14Br4O3
Mol. Mass.621.939
SMILESOc1c(Br)cc(\C=C2/CCC\C(=C/c3cc(Br)c(O)c(Br)c3)C2=O)cc1Br
Structure
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