| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM25904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_475794 (CHEMBL935619) |
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| Ki | 2633±n/a nM |
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| Citation |  Di Fiore, A; Pedone, C; Antel, J; Waldeck, H; Witte, A; Wurl, M; Scozzafava, A; Supuran, CT; De Simone, G Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. Bioorg Med Chem Lett18:2669-74 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII |
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| Type: | Enzyme |
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| Mol. Mass.: | 29522.80 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Murine cloned isozyme |
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| Residue: | 262 |
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| Sequence: | MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKII
SNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELH
VVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNF
DPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAA
FLLSNHRPPQPLKGRRVRASFY
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| BDBM25904 |
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| n/a |
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| Name | BDBM25904 |
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| Synonyms: | 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide | BMC173212 Compound 1 | CHEMBL262628 | indole sulfonamide, L |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O3S |
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| Mol. Mass. | 330.362 |
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| SMILES | NNC(=O)c1[nH]c2ccc(cc2c1-c1ccccc1)S(N)(=O)=O |
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| Structure | 
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