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TargetAdenosine receptor A1
LigandBDBM50239036
Substrate/Competitorn/a
Meas. Tech.ChEMBL_479714 (CHEMBL921474)
Ki 17±n/a nM
Citation Gillespie, RJCliffe, IADawson, CEDourish, CTGaur, SJordan, AMKnight, ARLerpiniere, JMisra, APratt, RMRoffey, JStratton, GCUpton, RWeiss, SMWilliamson, DS Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett18:2924-9 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36520.92
Organism:Homo sapiens (Human)
Description:P30542
Residue:326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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  Blast E-value cutoff:
BDBM50239036
n/a
NameBDBM50239036
Synonyms:2-amino-N-benzyl-6-(furan-2-yl)-9H-purine-9-carboxamide | CHEMBL261203
TypeSmall organic molecule
Emp. Form.C17H14N6O2
Mol. Mass.334.3321
SMILESNc1nc(-c2ccco2)c2ncn(C(=O)NCc3ccccc3)c2n1
Structure
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