| Reaction Details |
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 | Report a problem with these data |
| Target | Transient receptor potential cation channel subfamily A member 1 |
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| Ligand | BDBM50377664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_479898 (CHEMBL935751) |
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| EC50 | >100000±n/a nM |
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| Citation |  Ortar, G; Schiano Moriello, A; Cascio, MG; De Petrocellis, L; Ligresti, A; Morera, E; Nalli, M; Di Marzo, V New tetrazole-based selective anandamide uptake inhibitors. Bioorg Med Chem Lett18:2820-4 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transient receptor potential cation channel subfamily A member 1 |
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| Name: | Transient receptor potential cation channel subfamily A member 1 |
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| Synonyms: | Anktm1 | TRPA1_RAT | Trpa1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 128622.74 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1450487 |
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| Residue: | 1125 |
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| Sequence: | MKRSLRRVLRPEERKEVQGVVYRGVGKDMDCSKESFKVDIEGDMCRLEAFIKNRRKLSKY
EDENLCLLHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLS
QGANPNLRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSE
ALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKRCMELILAYGEKTGYSREAHINFVNHKK
ASPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSS
DIVNAVDGNQETLLHRASLFDHHDLADYLISVGADINSTDSEGRSPLILATASASWNIVN
LLLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFLQMQHIKELVMDEDNDGCTPLHY
ACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNEGD
LHGMTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLK
CTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTT
IRSKRWDECLQVFTHDSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYN
FKYLQCPLSMTKKVTPTQDVIYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRA
HMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTGIINETISTHEERINTLNSFPLKICMILV
FLSSIFGYCKEVVQIFQQKRNYFLDYNNALEWVIYTTSMIFVLPLFLDIPAYMQWQCGAI
AIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDA
FSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLI
GLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLPFWYLRKVDQRSTIVYPNRPRHGRMLR
FFHYFLSMQETRQEAPNIDTCLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISET
EDEDNHCSFQDRFKKERLEQMHSKWNFVLNAVKTKTHCSISHPDI
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| BDBM50377664 |
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| n/a |
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| Name | BDBM50377664 |
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| Synonyms: | CHEMBL402283 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N6O |
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| Mol. Mass. | 318.3327 |
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| SMILES | O=C(NCc1nnn(CC#N)n1)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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