| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50261175 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_533285 (CHEMBL973304) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Wentland, MP; Sun, X; Cohen, DJ; Bidlack, JM Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine. Bioorg Med Chem16:5653-64 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50261175 |
|---|
| n/a |
|---|
| Name | BDBM50261175 |
|---|
| Synonyms: | CHEMBL494613 | rac-(cis)-3-Cyclopropylmethyl-6,11-dimethyl-9-nitro-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H24N2O3 |
|---|
| Mol. Mass. | 316.3948 |
|---|
| SMILES | C[C@H]1C2Cc3cc(c(O)cc3[C@@]1(C)CCN2CC1CC1)[N+]([O-])=O |r,TLB:9:10:1:15.13.14,16:15:1:4.10.3| |
|---|
| Structure | 
|
|---|
Search and Browse
