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TargetMu-type opioid receptor
LigandBDBM50261176
Substrate/Competitorn/a
Meas. Tech.ChEMBL_533284 (CHEMBL973302)
Ki 20±n/a nM
Citation Wentland, MPSun, XCohen, DJBidlack, JM Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine. Bioorg Med Chem16:5653-64 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50261176
n/a
NameBDBM50261176
Synonyms:CHEMBL494614 | cis-(+/-)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-7-nitro-2,6-methano-3-benzazocine-8-carboxamide
TypeSmall organic molecule
Emp. Form.C19H25N3O3
Mol. Mass.343.4201
SMILESC[C@H]1C2Cc3ccc(C(N)=O)c(c3[C@@]1(C)CCN2CC1CC1)[N+]([O-])=O |r,TLB:11:12:1:17.15.16,18:17:1:4.12.3|
Structure
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