| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
|---|
| Ligand | BDBM50118213 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_552861 (CHEMBL958066) |
|---|
| EC50 | 60±n/a nM |
|---|
| Citation |  Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg Med Chem16:6319-32 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 2 |
|---|
| Name: | P2Y purinoceptor 2 |
|---|
| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42299.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1455361 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
|
|
|
|---|
| BDBM50118213 |
|---|
| n/a |
|---|
| Name | BDBM50118213 |
|---|
| Synonyms: | 5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(tetrahydrogen triphosphate) | uridine 5'-triphosphoric acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H15N2O15P3 |
|---|
| Mol. Mass. | 484.1411 |
|---|
| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
