| Reaction Details |
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 | Report a problem with these data |
| Target | Glycylpeptide N-tetradecanoyltransferase |
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| Ligand | BDBM50034993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_507080 (CHEMBL946589) |
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| IC50 | 24±n/a nM |
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| Citation |  Wu, J; Tao, Y; Zhang, M; Howard, MH; Gutteridge, S; Ding, J Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region. J Biol Chem282:22185-94 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycylpeptide N-tetradecanoyltransferase |
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| Name: | Glycylpeptide N-tetradecanoyltransferase |
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| Synonyms: | CDC72 | NMT1 | NMT_YEAST |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52840.42 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_507080 |
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| Residue: | 455 |
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| Sequence: | MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQPVKDFDEKVVEEGPID
KPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNENYVEDRDAGFRFNYTKEFF
NWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRGKQVPSVEINFLCVHKQLRSK
RLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCRYTHRPLNWKKLYEVDFTGLPDG
HTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELFKRYQSRFELIQIFTKEEFEHNFIG
EESLPLDKQVIFSYVVEQPDGKITDFFSFYSLPFTILNNTKYKDLGIGYLYYYATDADFQ
FKDRFDPKATKALKTRLCELIYDACILAKNANMDVFNALTSQDNTLFLDDLKFGPGDGFL
NFYLFNYRAKPITGGLNPDNSNDIKRRSNVGVVML
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| BDBM50034993 |
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| n/a |
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| Name | BDBM50034993 |
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| Synonyms: | (S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-hexanoic acid (2-cyclohexyl-ethyl)-amide | CHEMBL6269 | SC-58272 | [CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE |
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| Type | Small organic molecule |
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| Emp. Form. | C33H52N6O4 |
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| Mol. Mass. | 596.8038 |
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| SMILES | Cc1nccn1CCCCc1ccc(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 |
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| Structure | 
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