Reaction Details |
| Report a problem with these data |
Target | Myeloblastin |
---|
Ligand | BDBM50270031 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_508159 (CHEMBL1008217) |
---|
IC50 | 150±n/a nM |
---|
Citation | Méthot, N; Rubin, J; Guay, D; Beaulieu, C; Ethier, D; Reddy, TJ; Riendeau, D; Percival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Myeloblastin |
---|
Name: | Myeloblastin |
Synonyms: | PRTN3_MOUSE | Prtn3 |
Type: | PROTEIN |
Mol. Mass.: | 27628.93 |
Organism: | Mus musculus |
Description: | ChEMBL_508159 |
Residue: | 254 |
Sequence: | MSGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGG
TLIHPRFVLTAAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLND
VLLLQLNRTASLGKEVAVASLPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVV
TFLCREHNVCTLVPRRAAGICFGDSGGPLICNGILHGVDSFVIRECASLQFPDFFARVSM
YVDWIQNVLRGAEP
|
|
|
BDBM50270031 |
---|
n/a |
---|
Name | BDBM50270031 |
Synonyms: | 1-((1R,2R)-1-cyano-2-phenylcyclopropylamino)-3-(3-fluorothiophen-2-yl)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate | CHEMBL515494 |
Type | Small organic molecule |
Emp. Form. | C17H17FN3OS |
Mol. Mass. | 330.399 |
SMILES | [NH3+]C(Cc1sccc1F)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| |
Structure |
|