| Reaction Details |
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 | Report a problem with these data |
| Target | Myeloblastin |
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| Ligand | BDBM50269858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_508159 (CHEMBL1008217) |
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| IC50 | 4550±n/a nM |
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| Citation |  Méthot, N; Rubin, J; Guay, D; Beaulieu, C; Ethier, D; Reddy, TJ; Riendeau, D; Percival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Myeloblastin |
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| Name: | Myeloblastin |
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| Synonyms: | PRTN3_MOUSE | Prtn3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27628.93 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_508159 |
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| Residue: | 254 |
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| Sequence: | MSGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGG
TLIHPRFVLTAAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLND
VLLLQLNRTASLGKEVAVASLPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVV
TFLCREHNVCTLVPRRAAGICFGDSGGPLICNGILHGVDSFVIRECASLQFPDFFARVSM
YVDWIQNVLRGAEP
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| BDBM50269858 |
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| n/a |
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| Name | BDBM50269858 |
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| Synonyms: | Trifluoro-acetate(S)-1-((1S,2S)-1-cyano-2-phenyl-cyclopropylcarbamoyl)-2-(2-fluoro-phenyl)-ethyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19FN3O |
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| Mol. Mass. | 324.3715 |
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| SMILES | [NH3+][C@@H](Cc1ccccc1F)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N |r| |
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| Structure | 
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