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TargetMyeloblastin
LigandBDBM50052693
Substrate/Competitorn/a
Meas. Tech.ChEMBL_508159 (CHEMBL1008217)
IC50>10000±n/a nM
Citation Méthot, NRubin, JGuay, DBeaulieu, CEthier, DReddy, TJRiendeau, DPercival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Myeloblastin
Name:Myeloblastin
Synonyms:PRTN3_MOUSE | Prtn3
Type:PROTEIN
Mol. Mass.:27628.93
Organism:Mus musculus
Description:ChEMBL_508159
Residue:254
Sequence:
MSGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGG
TLIHPRFVLTAAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLND
VLLLQLNRTASLGKEVAVASLPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVV
TFLCREHNVCTLVPRRAAGICFGDSGGPLICNGILHGVDSFVIRECASLQFPDFFARVSM
YVDWIQNVLRGAEP
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BDBM50052693
n/a
NameBDBM50052693
Synonyms:(2S,3S)-3-[(S)-3-Methyl-1-(3-methyl-butylcarbamoyl)-butylcarbamoyl]-oxirane-2-carboxylic acid ethyl ester | (2S,3S)-ethyl 3-(((S)-1-(isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylate | (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester | 3-[3-Methyl-1-(3-methyl-butylcarbamoyl)-butylcarbamoyl]-oxirane-2-carboxylic acid ethyl ester | Aloxistatin | CHEMBL63440
TypeSmall organic molecule
Emp. Form.C17H30N2O5
Mol. Mass.342.4305
SMILESCCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C |r|
Structure
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