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TargetBeta-1 adrenergic receptor
LigandBDBM50246936
Substrate/Competitorn/a
Meas. Tech.ChEMBL_528528 (CHEMBL972063)
EC50 1.8±n/a nM
Citation Gafner, S; Dietz, BM; McPhail, KL; Scott, IM; Glinski, JA; Russell, FE; McCollom, MM; Budzinski, JW; Foster, BC; Bergeron, C; Rhyu, MR; Bolton, JL Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. J Nat Prod69:432-5 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-1 adrenergic receptor
Name:Beta-1 adrenergic receptor
Synonyms:ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | adrenergic Beta1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51338.40
Organism:Homo sapiens (Human)
Description:P08588
Residue:477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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  Blast E-value cutoff:
BDBM50246936
n/a
NameBDBM50246936
Synonyms:(-)-(S)-Propranolol | 1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL | CHEMBL452861 | PROPRANOLOL | S-(-)-propanolol | [2-Hydroxy-3-(naphthalen-1-yloxy)-propyl]-isopropyl-ammonium((-)-propranolol)
TypeSmall organic molecule
Emp. Form.C16H21NO2
Mol. Mass.259.3434
SMILESCC(C)NC[C@H](O)COc1cccc2ccccc12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: