| Reaction Details |
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 | Report a problem with these data |
| Target | Nischarin |
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| Ligand | BDBM50262238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_490890 (CHEMBL989166) |
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| Ki | 232±n/a nM |
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| Citation |  Nikolic, K; Filipic, S; Agbaba, D QSAR study of imidazoline antihypertensive drugs. Bioorg Med Chem16:7134-40 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nischarin |
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| Name: | Nischarin |
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| Synonyms: | IRAS | Imidazoline I2 | Imidazoline receptor 1 (I1R) | KIAA0975 | NISCH | NISCH_HUMAN | Nischarin |
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| Type: | Enzyme |
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| Mol. Mass.: | 166571.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y2I1 |
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| Residue: | 1504 |
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| Sequence: | MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVS
EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC
SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ
DFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPP
DVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQG
SIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCL
VLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLT
FYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEA
VKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCT
QPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTG
GSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEA
STSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGS
AIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFS
EPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTR
DSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYP
SEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEI
FLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGH
DLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPV
ELTG
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| BDBM50262238 |
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| n/a |
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| Name | BDBM50262238 |
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| Synonyms: | 2-(4-Chloro-1,3-dihydro-isoindol-2-ylamino)-4,5-dihydro-3H-imidazol-1-ium |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14ClN4 |
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| Mol. Mass. | 237.708 |
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| SMILES | Clc1cccc2-[#6]-[#7](-[#6]-c12)\[#7+]=[#6]-1/[#7]-[#6]-[#6]-[#7]-1 |
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| Structure | 
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