| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 4 |
|---|
| Ligand | BDBM50262422 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_514536 (CHEMBL968890) |
|---|
| IC50 | 73000±n/a nM |
|---|
| Citation |  Brunschweiger, A; Iqbal, J; Umbach, F; Scheiff, AB; Munkonda, MN; Sévigny, J; Knowles, AF; Müller, CE Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide. J Med Chem51:4518-28 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 4 |
|---|
| Name: | P2Y purinoceptor 4 |
|---|
| Synonyms: | NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40977.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_751027 |
|---|
| Residue: | 365 |
|---|
| Sequence: | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
|
|
|
|---|
| BDBM50262422 |
|---|
| n/a |
|---|
| Name | BDBM50262422 |
|---|
| Synonyms: | CHEMBL477339 | sodium (E)-4-((3-formyl-4-hydroxy-5-methyl-2-(phosphonatooxymethyl)phenyl)diazenyl)benzene-1,3-disulfonate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H11N2O12PS2 |
|---|
| Mol. Mass. | 506.36 |
|---|
| SMILES | Cc1cc(N=Nc2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O |w:4.3| |
|---|
| Structure | 
|
|---|
Search and Browse
