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TargetCarbonic anhydrase 5B, mitochondrial
LigandBDBM15222
Substrate/Competitorn/a
Meas. Tech.ChEMBL_514689 (CHEMBL976461)
Ki 55.8±n/a nM
Citation Poulsen, SAWilkinson, BLInnocenti, AVullo, DSupuran, CT Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives. Bioorg Med Chem Lett18:4624-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 5B, mitochondrial
Name:Carbonic anhydrase 5B, mitochondrial
Synonyms:CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB)
Type:Enzyme
Mol. Mass.:36440.83
Organism:Homo sapiens (Human)
Description:Human (cloned) isozyme
Residue:317
Sequence:
MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
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  Blast E-value cutoff:
BDBM15222
n/a
NameBDBM15222
Synonyms:4-Azidobenzenesulfonamide | 4-azidobenzene-1-sulfonamide | CHEMBL222837 | azide 1
TypeSmall organic molecule
Emp. Form.C6H6N4O2S
Mol. Mass.198.202
SMILESNS(=O)(=O)c1ccc(cc1)N=[N+]=[N-]
Structure
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