| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5A, mitochondrial |
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| Ligand | BDBM50262063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514688 (CHEMBL976460) |
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| Ki | 12.8±n/a nM |
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| Citation |  Poulsen, SA; Wilkinson, BL; Innocenti, A; Vullo, D; Supuran, CT Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives. Bioorg Med Chem Lett18:4624-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5A, mitochondrial |
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| Name: | Carbonic anhydrase 5A, mitochondrial |
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| Synonyms: | CA-VA | CA5 | CA5A | CAH5A_HUMAN | Carbonate dehydratase VA | Carbonic Anhydrase VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase 5A, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VA (CA VA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34755.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 305 |
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| Sequence: | MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPG
GTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPL
ENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVI
GVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLT
ESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATN
EGTRS
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| BDBM50262063 |
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| n/a |
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| Name | BDBM50262063 |
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| Synonyms: | 4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide | CHEMBL469220 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O2S |
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| Mol. Mass. | 314.362 |
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| SMILES | Cc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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