| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
|---|
| Ligand | BDBM50249188 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_537531 (CHEMBL987100) |
|---|
| IC50 | 42000±n/a nM |
|---|
| Citation |  Arai, MA; Tateno, C; Hosoya, T; Koyano, T; Kowithayakorn, T; Ishibashi, M Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana. Bioorg Med Chem16:9420-4 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Zinc finger protein GLI1 |
|---|
| Name: | Zinc finger protein GLI1 |
|---|
| Synonyms: | GLI | GLI1 | GLI1_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 117920.33 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_537531 |
|---|
| Residue: | 1106 |
|---|
| Sequence: | MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQANLMSGPHSYGPARETN
SCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPGGS
YGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLK
SELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWD
GCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP
HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK
PYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREG
GPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSS
LDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLE
RRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGG
TSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSL
GCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNP
YMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETW
GEFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEG
PPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCN
YVQSQQELLWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHK
SGSYPTPSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLG
GGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGP
PNMAVGNMSVLLRSLPGETEFLNSSA
|
|
|
|---|
| BDBM50249188 |
|---|
| n/a |
|---|
| Name | BDBM50249188 |
|---|
| Synonyms: | Alphitolic acid | CHEMBL511805 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H48O4 |
|---|
| Mol. Mass. | 472.6997 |
|---|
| SMILES | CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
