Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50027791 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_558748 (CHEMBL1019877) |
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Ki | 5±n/a nM |
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Citation | Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Syntheses and opioid receptor binding properties of carboxamido-substituted opioids. Bioorg Med Chem Lett19:203-8 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50027791 |
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n/a |
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Name | BDBM50027791 |
Synonyms: | 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(phenazocine) | CHEMBL46399 | PHENAZOCINE |
Type | Small organic molecule |
Emp. Form. | C22H27NO |
Mol. Mass. | 321.4559 |
SMILES | CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1 |TLB:16:15:1:4.10.3,9:10:1:15.14.13| |
Structure |
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