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TargetSolute carrier family 22 member 1
LigandBDBM50240370
Substrate/Competitorn/a
Meas. Tech.ChEMBL_534654 (CHEMBL994103)
IC50 28600±n/a nM
Citation Ahlin, GKarlsson, JPedersen, JMGustavsson, LLarsson, RMatsson, PNorinder, UBergström, CAArtursson, P Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem51:5932-42 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Solute carrier family 22 member 1
Name:Solute carrier family 22 member 1
Synonyms:Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1
Type:Enzyme Catalytic Domain
Mol. Mass.:61154.85
Organism:Homo sapiens (Human)
Description:Adrenergic Alpha 0 HUMAN::O15245
Residue:554
Sequence:
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
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  Blast E-value cutoff:
BDBM50240370
n/a
NameBDBM50240370
Synonyms:1-(2-(allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol (Oxprenolol) | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol(oxprenolol) | CHEMBL546 | OXPRENOLOL | Trasicor
TypeSmall organic molecule
Emp. Form.C15H23NO3
Mol. Mass.265.348
SMILESCC(C)NCC(O)COc1ccccc1OCC=C
Structure
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