| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM50080092 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_534654 (CHEMBL994103) |
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| IC50 | 35100±n/a nM |
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| Citation |  Ahlin, G; Karlsson, J; Pedersen, JM; Gustavsson, L; Larsson, R; Matsson, P; Norinder, U; Bergström, CA; Artursson, P Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem51:5932-42 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 61154.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Adrenergic Alpha 0 HUMAN::O15245 |
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| Residue: | 554 |
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| Sequence: | MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
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| BDBM50080092 |
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| n/a |
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| Name | BDBM50080092 |
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| Synonyms: | (17beta)-17-hydroxyestr-4-en-3-one | 17beta-hydroxy-19-nor-4-androsten-3-one | 17beta-hydroxy-4-estren-3-one | 17beta-hydroxyestr-4-en-3-one | 19-Norandrostenolone | 19-Nortestosterone | 4-estren-17beta-ol-3-one | CHEMBL757 | Nandrolone |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26O2 |
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| Mol. Mass. | 274.3978 |
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| SMILES | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@H]2O |r,t:8| |
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| Structure | 
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