| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
|---|
| Ligand | BDBM22319 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_494689 (CHEMBL938648) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Seierstad, M; Breitenbucher, JG Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors. J Med Chem51:7327-43 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fatty-acid amide hydrolase 1 |
|---|
| Name: | Fatty-acid amide hydrolase 1 |
|---|
| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 63071.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O00519 |
|---|
| Residue: | 579 |
|---|
| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
|
|
|
|---|
| BDBM22319 |
|---|
| n/a |
|---|
| Name | BDBM22319 |
|---|
| Synonyms: | (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | Arachidonic acid | Arachidonic acid (AA) | CHEMBL15594 | [1-14C]Arachidonic acid |
|---|
| Type | Unsaturated fatty acid |
|---|
| Emp. Form. | C20H32O2 |
|---|
| Mol. Mass. | 304.4669 |
|---|
| SMILES | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
