| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Ligand | BDBM50275262 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_494697 (CHEMBL938656) |
|---|
| Ki | 420±n/a nM |
|---|
| Citation |  Hansen, CP; Jensen, AA; Christensen, JK; Balle, T; Liljefors, T; Frølund, B Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist. J Med Chem51:7380-95 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Synonyms: | ACHA3_RAT | Acra3 | Chrna3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56995.52 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P04757 |
|---|
| Residue: | 499 |
|---|
| Sequence: | MGVVLLPPPLSMLMLVLMLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEV
SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNN
ADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK
IDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTI
NLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGE
YLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSGEGDT
PKTRTFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSE
SVNAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILV
CILGTAGLFLQPLMARDDT
|
|
|
|---|
| BDBM50275262 |
|---|
| n/a |
|---|
| Name | BDBM50275262 |
|---|
| Synonyms: | 3-(dimethylamino)butyl dimethylcarbamate | 3-N,N-dimethylaminobutyl-N,N-dimethylcarbamate | CHEMBL486572 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H20N2O2 |
|---|
| Mol. Mass. | 188.2673 |
|---|
| SMILES | CC(CCOC(=O)N(C)C)N(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
