| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50412930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_515099 (CHEMBL1035607) |
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| Ki | 15.85±n/a nM |
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| Citation |  Bellenie, BR; Barton, NP; Emmons, AJ; Heer, JP; Salvagno, C Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug design. Bioorg Med Chem Lett19:990-4 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50412930 |
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| n/a |
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| Name | BDBM50412930 |
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| Synonyms: | CHEMBL482323 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26FNO2 |
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| Mol. Mass. | 403.4885 |
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| SMILES | Cc1cc(F)ccc1-c1ccc(cc1)C(=O)N(CC1CCCO1)Cc1ccccc1 |
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| Structure | 
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