| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50185957 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_516175 (CHEMBL984215) |
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| Ki | 0.92±n/a nM |
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| Citation |  Scarf, AM; Ittner, LM; Kassiou, M The translocator protein (18 kDa): central nervous system disease and drug design. J Med Chem52:581-92 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo |
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| Type: | Mitochondrion membrane protein |
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| Mol. Mass.: | 18945.84 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competitive binding experiments were performed on rat kidney mitochondrial membranes. |
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| Residue: | 169 |
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| Sequence: | MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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| BDBM50185957 |
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| n/a |
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| Name | BDBM50185957 |
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| Synonyms: | CHEMBL205767 | N-(2-isopropoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)acetamide | N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl)acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24ClNO3 |
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| Mol. Mass. | 409.905 |
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| SMILES | CC(C)Oc1ccccc1CN(C(C)=O)c1ccc(Cl)cc1Oc1ccccc1 |
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| Structure | 
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