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TargetCation-dependent mannose-6-phosphate receptor
LigandBDBM50275808
Substrate/Competitorn/a
Meas. Tech.ChEMBL_492874 (CHEMBL942205)
IC50 22000±n/a nM
Citation Jeanjean, AGary-Bobo, MNirdé, PLeiris, SGarcia, MMorère, A Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett18:6240-3 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cation-dependent mannose-6-phosphate receptor
Name:Cation-dependent mannose-6-phosphate receptor
Synonyms:M6PR | MPR46 | MPRD | MPRD_HUMAN
Type:PROTEIN
Mol. Mass.:30989.41
Organism:Homo sapiens (Human)
Description:ChEMBL_492874
Residue:277
Sequence:
MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF
ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML
IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC
DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50275808
n/a
NameBDBM50275808
Synonyms:CHEMBL470777 | sodium-2-((2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)vinylphosphonate
TypeSmall organic molecule
Emp. Form.C8H13O8P
Mol. Mass.268.1589
SMILESCO[C@H]1O[C@H](\C=C\P([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure
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