| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50248969 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543319 (CHEMBL1022989) |
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| Ki | 1.3±n/a nM |
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| Citation |  Moynihan, H; Jales, AR; Greedy, BM; Rennison, D; Broadbear, JH; Purington, L; Traynor, JR; Woods, JH; Lewis, JW; Husbands, SM 14 beta-O-cinnamoylnaltrexone and related dihydrocodeinones are mu opioid receptor partial agonists with predominant antagonist activity. J Med Chem52:1553-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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|
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| BDBM50248969 |
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| n/a |
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| Name | BDBM50248969 |
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| Synonyms: | 14beta-(4-Chlorocinnamoyloxy)-N-cyclopropylmethyl-7,8-dihydronormorphinone | CHEMBL514927 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28ClNO5 |
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| Mol. Mass. | 505.989 |
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| SMILES | Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35OC(=O)\C=C\c1ccc(Cl)cc1 |r| |
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| Structure | 
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