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TargetCarbonic anhydrase 7
LigandBDBM25904
Substrate/Competitorn/a
Meas. Tech.ChEMBL_565861
Ki 89±n/a nM
Citation Crocetti LMaresca ATemperini CHall RAScozzafava AMühlschlegel FASupuran CT A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. Bioorg Med Chem Lett 19:1371-5 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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BDBM25904
n/a
NameBDBM25904
Synonyms:2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide | BMC173212 Compound 1 | CHEMBL262628 | indole sulfonamide, L
TypeSmall organic molecule
Emp. Form.C15H14N4O3S
Mol. Mass.330.362
SMILESNNC(=O)c1[nH]c2ccc(cc2c1-c1ccccc1)S(N)(=O)=O
Structure
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