| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic Anhydrase XIV |
|---|
| Ligand | BDBM50248167 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_565865 |
|---|
| Ki | 424±n/a nM |
|---|
| Citation |  Crocetti L; Maresca A; Temperini C; Hall RA; Scozzafava A; Mühlschlegel FA; Supuran CT A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. Bioorg Med Chem Lett 19:1371-5 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic Anhydrase XIV |
|---|
| Name: | Carbonic Anhydrase XIV |
|---|
| Synonyms: | CA-XIV | Carbonate dehydratase XIV | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37665.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme. |
|---|
| Residue: | 337 |
|---|
| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
|
|
|
|---|
| BDBM50248167 |
|---|
| n/a |
|---|
| Name | BDBM50248167 |
|---|
| Synonyms: | 2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide | 2-(thiazol-4-yl)-1H-benzo[d]imidazole-5-sulfonamide | CHEMBL455271 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H8N4O2S2 |
|---|
| Mol. Mass. | 280.326 |
|---|
| SMILES | NS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cscn1 |
|---|
| Structure | 
|
|---|
Search and Browse
