| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50266962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563708 (CHEMBL992672) |
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| Ki | >1000±n/a nM |
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| Citation |  Yang, L; Xu, W; Chen, F; Liu-Chen, LY; Ma, Z; Lee, DY Synthesis and biological evaluation of C-12 triazole and oxadiazole analogs of salvinorin A. Bioorg Med Chem Lett19:1301-4 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50266962 |
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| n/a |
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| Name | BDBM50266962 |
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| Synonyms: | (2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1-(pivaloyloxymethyl)-1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate | CHEMBL474477 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37N3O9 |
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| Mol. Mass. | 547.5974 |
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| SMILES | COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1cn(COC(=O)C(C)(C)C)nn1 |r| |
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| Structure | 
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