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TargetTranslocator protein
LigandBDBM50266861
Substrate/Competitorn/a
Meas. Tech.ChEMBL_563773 (CHEMBL993536)
Ki 0.49±n/a nM
Citation Yanamoto, KKumata, KYamasaki, TOdawara, CKawamura, KYui, JHatori, ASuzuki, KZhang, MR [18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain. Bioorg Med Chem Lett19:1707-10 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50266861
n/a
NameBDBM50266861
Synonyms:CHEMBL515622 | N-benzyl-N-ethyl-2-(7-(2-fluoroethyl)-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide
TypeSmall organic molecule
Emp. Form.C24H24FN5O2
Mol. Mass.433.4781
SMILESCCN(Cc1ccccc1)C(=O)Cn1c2nc(ncc2n(CCF)c1=O)-c1ccccc1
Structure
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