| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50278520 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_565043 (CHEMBL959186) |
|---|
| Ki | 1370±n/a nM |
|---|
| Citation |  Behrenswerth, A; Volz, N; Toräng, J; Hinz, S; Bräse, S; Müller, CE Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists. Bioorg Med Chem17:2842-51 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52856.55 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P20272 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50278520 |
|---|
| n/a |
|---|
| Name | BDBM50278520 |
|---|
| Synonyms: | 1-(6-(1,3-dithiolan-2-yl)-2,2-dimethyl-2H-chromen-5-yl) 3-ethyl 2-(3-phenylallylidene)malonate | CHEMBL512509 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H28O5S2 |
|---|
| Mol. Mass. | 508.649 |
|---|
| SMILES | CCOC(=O)C(=C\C=C\c1ccccc1)\C(=O)Oc1c(ccc2OC(C)(C)C=Cc12)C1SCCS1 |c:28| |
|---|
| Structure | 
|
|---|
Search and Browse
