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TargetMu-type opioid receptor
LigandBDBM50241341
Substrate/Competitorn/a
Meas. Tech.ChEMBL_565185 (CHEMBL958391)
Ki 0.280000±n/a nM
Citation Wentland, MPLou, RLu, QBu, YDenhardt, CJin, JGanorkar, RVanAlstine, MAGuo, CCohen, DJBidlack, JM Syntheses of novel high affinity ligands for opioid receptors. Bioorg Med Chem Lett19:2289-94 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50241341
n/a
NameBDBM50241341
Synonyms:(-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one | 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one | 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one | 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone | 6-Deoxy-7,8-dihydro-6-oxomorphine | 7,8-Dihydromorphinone | CHEMBL398707 | Dihydromorfinon | Dihydromorphinone | Dimorphone | HYDROMORPHONE | Hydromorfona | Hydromorphone Hydrochloride | Idromorfone
TypeSmall organic molecule
Emp. Form.C17H19NO3
Mol. Mass.285.3377
SMILESCN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3CCC4=O)ccc5O |r|
Structure
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