| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hydroxycarboxylic acid receptor 2 |
|---|
| Ligand | BDBM50277789 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_501319 (CHEMBL971505) |
|---|
| IC50 | 70±n/a nM |
|---|
| Citation |  Imbriglio, JE; Chang, S; Liang, R; Raghavan, S; Schmidt, D; Smenton, A; Tria, S; Schrader, TO; Jung, JK; Esser, C; Taggart, AK; Cheng, K; Carballo-Jane, E; Gerard Waters, M; Tata, JR; Colletti, SL GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole-tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a. Bioorg Med Chem Lett19:2121-4 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Hydroxycarboxylic acid receptor 2 |
|---|
| Name: | Hydroxycarboxylic acid receptor 2 |
|---|
| Synonyms: | Gpr109 | Gpr109a | Gpr109b | HCAR2_MOUSE | HM74 nicotinic acid GPCR | Hcar2 | Niacr1 | Pumag |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41418.01 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_820676 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MSKSDHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSR
IFLFNLAVADFLLIICLPFLTDNYVHNWDWRFGGIPCRVMLFMLAMNRQGSIIFLTVVAV
DRYFRVVHPHHFLNKISNRTAAIISCFLWGLTIGLTVHLLYTNMMTKNGEAYLCSSFSIC
YNFRWHDAMFLLEFFLPLAIILFCSGRIIWSLRQRQMDRHAKIKRAINFIMVVAIVFIIC
FLPSVAVRIRIFWLLYKYNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPN
FFSTCINRCLRKKTLGEPDNNRSTSVELTGDPSTTRSIPGALMADPSEPGSPPYLASTSR
|
|
|
|---|
| BDBM50277789 |
|---|
| n/a |
|---|
| Name | BDBM50277789 |
|---|
| Synonyms: | 3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole | CHEMBL520137 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H9F3N6 |
|---|
| Mol. Mass. | 306.246 |
|---|
| SMILES | Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
