| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
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| Ligand | BDBM50155556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_544670 (CHEMBL1009247) |
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| Ki | 6.5±n/a nM |
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| Citation |  Thiry, A; Rolin, S; Vullo, D; Frankart, A; Scozzafava, A; Dogné, JM; Wouters, J; Supuran, CT; Masereel, B Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. Eur J Med Chem43:2853-60 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 14 |
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| Name: | Carbonic anhydrase 14 |
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| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37665.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme. |
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| Residue: | 337 |
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| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
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| BDBM50155556 |
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| n/a |
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| Name | BDBM50155556 |
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| Synonyms: | 2,3-dihydro-1H-indene-5-sulfonamide | CHEMBL364869 | Indan-5-sulfonic acid amide | indane-5-sulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11NO2S |
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| Mol. Mass. | 197.254 |
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| SMILES | NS(=O)(=O)c1ccc2CCCc2c1 |
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| Structure | 
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