| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50155553 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_544671 (CHEMBL1009248) |
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| Ki | 1.6±n/a nM |
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| Citation |  Thiry, A; Rolin, S; Vullo, D; Frankart, A; Scozzafava, A; Dogné, JM; Wouters, J; Supuran, CT; Masereel, B Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. Eur J Med Chem43:2853-60 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50155553 |
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| n/a |
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| Name | BDBM50155553 |
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| Synonyms: | 2-Amino-indan-5-sulfonic acid amide; hydrochloride | CHEMBL457996 | CHEMBL559179 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12N2O2S |
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| Mol. Mass. | 212.269 |
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| SMILES | NC1Cc2ccc(cc2C1)S(N)(=O)=O |
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| Structure | 
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