| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50227023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_498707 (CHEMBL971541) |
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| EC50 | 80.4±n/a nM |
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| Citation |  Hillmann, P; Ko, GY; Spinrath, A; Raulf, A; von Kügelgen, I; Wolff, SC; Nicholas, RA; Kostenis, E; Höltje, HD; Müller, CE Key determinants of nucleotide-activated G protein-coupled P2Y(2) receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling. J Med Chem52:2762-75 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50227023 |
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| n/a |
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| Name | BDBM50227023 |
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| Synonyms: | 1-amino-4-(4-methoxyphenyl)-2-sulfoanthraquinone | CHEMBL401735 | SB-416 | sodium 1-amino-4-(4-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15N2O6S |
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| Mol. Mass. | 423.419 |
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| SMILES | COc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1 |
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| Structure | 
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