| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50205413 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_498707 (CHEMBL971541) |
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| EC50 | 112±n/a nM |
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| Citation |  Hillmann, P; Ko, GY; Spinrath, A; Raulf, A; von Kügelgen, I; Wolff, SC; Nicholas, RA; Kostenis, E; Höltje, HD; Müller, CE Key determinants of nucleotide-activated G protein-coupled P2Y(2) receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling. J Med Chem52:2762-75 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50205413 |
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| n/a |
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| Name | BDBM50205413 |
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| Synonyms: | CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraphosphate | P1,P4-Bis(5'-uridyl) tetrahydrogen tetraphosphate |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N4O23P4 |
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| Mol. Mass. | 790.3071 |
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| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| |
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| Structure | 
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