| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50378032 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_499481 (CHEMBL1021973) |
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| IC50 | 1900±n/a nM |
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| Citation |  Martins, FT; Assis, DM; Dos Santos, MH; Camps, I; Veloso, MP; Juliano, MA; Alves, LC; Doriguetto, AC Natural polyprenylated benzophenones inhibiting cysteine and serine proteases. Eur J Med Chem44:1230-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50378032 |
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| n/a |
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| Name | BDBM50378032 |
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| Synonyms: | CHEMBL452483 | Guttiferone A |
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| Type | Small organic molecule |
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| Emp. Form. | C38H50O6 |
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| Mol. Mass. | 602.8 |
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| SMILES | [#6]\[#6](-[#6])=[#6]/[#6]-[#6][C@]1([#6])[#6@@H](-[#6]\[#6]=[#6](/[#6])-[#6])-[#6][C@@]2([#6]\[#6]=[#6](/[#6])-[#6])[#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6](=O)[C@]1([#6]\[#6]=[#6](/[#6])-[#6])[#6]2=O |r,TLB:43:42:6.8.14:21.23.34| |
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| Structure | 
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