| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
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| Ligand | BDBM50378033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_499799 (CHEMBL972431) |
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| IC50 | 660±n/a nM |
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| Citation |  Mahindroo, N; Punchihewa, C; Fujii, N Hedgehog-Gli signaling pathway inhibitors as anticancer agents. J Med Chem52:3829-45 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc finger protein GLI1 |
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| Name: | Zinc finger protein GLI1 |
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| Synonyms: | GLI | GLI1 | GLI1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 117920.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_537531 |
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| Residue: | 1106 |
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| Sequence: | MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQANLMSGPHSYGPARETN
SCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPGGS
YGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLK
SELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWD
GCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP
HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK
PYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREG
GPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSS
LDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLE
RRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGG
TSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSL
GCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNP
YMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETW
GEFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEG
PPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCN
YVQSQQELLWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHK
SGSYPTPSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLG
GGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGP
PNMAVGNMSVLLRSLPGETEFLNSSA
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| BDBM50378033 |
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| n/a |
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| Name | BDBM50378033 |
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| Synonyms: | PHYSALIN F |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30O10 |
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| Mol. Mass. | 526.5318 |
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| SMILES | C[C@@]12OC(=O)[C@]3(O)CC[C@H]4[C@@H](C[C@H]5O[C@]55CC=CC(=O)[C@]45C)[C@@]45O[C@@]13[C@@H](C4=O)[C@]1(C)C[C@H]2OC(=O)[C@@H]1CO5 |r,c:17,TLB:33:35:26:24.23,30:28:26:24.23,THB:29:28:26:24.23| |
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| Structure | 
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