| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
|---|
| Ligand | BDBM50295173 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_576148 (CHEMBL1027137) |
|---|
| IC50 | >50000±n/a nM |
|---|
| Citation |  Sashidhara, KV; White, KN; Crews, P A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products. J Nat Prod72:588-603 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Methionine aminopeptidase 2 |
|---|
| Name: | Methionine aminopeptidase 2 |
|---|
| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52884.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P50579 |
|---|
| Residue: | 478 |
|---|
| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
|
|
|
|---|
| BDBM50295173 |
|---|
| n/a |
|---|
| Name | BDBM50295173 |
|---|
| Synonyms: | Bengamide O | CHEMBL539894 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H60N2O8 |
|---|
| Mol. Mass. | 612.8381 |
|---|
| SMILES | CCC(C)CCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)\C=C\C(C)C)C(=O)N(C)C1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
