| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM50113436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_576148 |
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| IC50 | 30±n/a nM |
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| Citation |  Sashidhara KV; White KN; Crews P A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products. J Nat Prod 72:588-603 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Aminopeptidase |
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| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | Peptidase M 2 | p67 | p67eIF2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52884.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 478 |
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| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
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| BDBM50113436 |
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| n/a |
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| Name | BDBM50113436 |
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| Synonyms: | CHEMBL32838 | fumagillin |
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| Type | Small organic molecule |
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| Emp. Form. | C26H34O7 |
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| Mol. Mass. | 458.544 |
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| SMILES | [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](/[#6])-[#6])-[#8]-[#6](=O)\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6](-[#8])=O |
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| Structure | 
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