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TargetNeprilysin [1-24]
LigandBDBM50046258
Substrate/Competitorn/a
Meas. Tech.ChEMBL_585130 (CHEMBL1060019)
IC50 50±n/a nM
Citation Olimpieri, FTambaro, SFustero, SLazzari, PSanchez-Roselló, MPani, LVolonterio, AZanda, M Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors. Bioorg Med Chem Lett19:4715-9 (2009) [PubMed]  Article
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Neprilysin [1-24]
Name:Neprilysin [1-24]
Synonyms:MME | NEP_PIG | Neprilysin
Type:PROTEIN
Mol. Mass.:2817.48
Organism:Sus scrofa
Description:ChEMBL_585130
Residue:24
Sequence:
PKPKKKQRWTPLEISLEVLVLVLV
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BDBM50046258
n/a
NameBDBM50046258
Synonyms:3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hexanoylamino)-3-phenyl-propionylamino]-propionic acid | 3-(4-hydroxyphenyl)-2-(2-(3-mercapto-5-methylhexanamido)-3-phenylpropanamido)propanoic acid | CHEMBL367174
TypeSmall organic molecule
Emp. Form.C25H32N2O5S
Mol. Mass.472.597
SMILESCC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O
Structure
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