| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase BRSK2 |
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| Ligand | BDBM50298223 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_587227 (CHEMBL1061990) |
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| IC50 | 1100±n/a nM |
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| Citation |  Bain, J; Plater, L; Elliott, M; Shpiro, N; Hastie, CJ; McLauchlan, H; Klevernic, I; Arthur, JS; Alessi, DR; Cohen, P The selectivity of protein kinase inhibitors: a further update. Biochem J408:297-315 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase BRSK2 |
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| Name: | Serine/threonine-protein kinase BRSK2 |
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| Synonyms: | BR serine/threonine-protein kinase 2 | BRSK2 | BRSK2_HUMAN | C11orf7 | PEN11B | SADA | STK29 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 81657.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_586949 |
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| Residue: | 736 |
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| Sequence: | MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVL
MKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARK
FFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPH
YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIP
PDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDP
DVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRNEIDP
PRKRVDSPMLNRHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGASSGL
STSPLSSPRVTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVPWRARLN
SIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKD
KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATGGPAVFQKPVKFQVDITYTEGGE
AQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDPPAAQHLSDTTNCMEMMTGRLS
KCGSPLSNFFDVIKQLFSDEKNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPGGDAEYPTG
KDTAKMGPPTARREQP
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| BDBM50298223 |
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| n/a |
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| Name | BDBM50298223 |
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| Synonyms: | CGP-57380 | CHEMBL1240885 | CHEMBL576817 | N-(4-fluorophenyl)-3H-pyrazolo[3,4-d]pyrimidine-3,4-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C11H9FN6 |
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| Mol. Mass. | 244.2278 |
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| SMILES | Nc1ncnc2n[nH]c(Nc3ccc(F)cc3)c12 |
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| Structure | 
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