Citation | Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Brizzi, A; Pasquini, S; Lavecchia, A; Allarà, M; Fantini, N; Carai, MA; Novellino, E; Colombo, G; Di Marzo, V; Corelli, F Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile. Bioorg Med Chem17:5549-64 (2009) [PubMed] Article |
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SMILES | Cc1ccc(C)n1-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)Nc1ccc(Cl)cc1 |(27.87,-23.36,;28.77,-22.11,;30.3,-22.09,;30.77,-20.63,;29.51,-19.74,;29.5,-18.2,;28.28,-20.65,;26.81,-20.18,;26.33,-18.72,;27.23,-17.47,;24.78,-18.74,;24.33,-20.2,;25.58,-21.1,;25.59,-22.64,;26.93,-23.39,;26.94,-24.93,;25.61,-25.72,;25.62,-27.25,;24.28,-24.95,;24.26,-23.41,;22.93,-22.66,;23.88,-17.5,;24.49,-16.09,;22.35,-17.67,;21.43,-16.44,;19.9,-16.61,;18.99,-15.37,;19.61,-13.96,;18.69,-12.72,;21.13,-13.79,;22.04,-15.03,)| |