| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM10862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_588928 (CHEMBL1063843) |
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| Ki | 28900±n/a nM |
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| Citation |  Carta, F; Maresca, A; Covarrubias, AS; Mowbray, SL; Jones, TA; Supuran, CT Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. Bioorg Med Chem Lett19:6649-54 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | β-Carbonic anhydrase 2 (CA 2) | Carbonic anhydrase | MTCA2_MYCTU | canB | cynT | mtcA2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 21788.97 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WPJ9 |
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| Residue: | 207 |
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| Sequence: | MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEI
IFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDG
TLPGGYVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILMARSSAISERIAGGSL
AIVGVTYQLDDGRAVLRDHIGNIGEEV
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| BDBM10862 |
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| n/a |
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| Name | BDBM10862 |
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| Synonyms: | 4-Amino-3-fluorobenzenesulfonamide | 4-amino-3-fluorobenzene-1-sulfonamide | CHEMBL6853 | aromatic/heteroaromatic sulfonamide 7 | halogenosulfanilamide deriv. 5b |
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| Type | Small organic molecule |
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| Emp. Form. | C6H7FN2O2S |
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| Mol. Mass. | 190.195 |
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| SMILES | Nc1ccc(cc1F)S(N)(=O)=O |
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| Structure | 
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