| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 15 |
|---|
| Ligand | BDBM10888 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_592895 (CHEMBL1048398) |
|---|
| Ki | 634±n/a nM |
|---|
| Citation |  Temperini, C; Innocenti, A; Scozzafava, A; Parkkila, S; Supuran, CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem53:850-4 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 15 |
|---|
| Name: | Carbonic anhydrase 15 |
|---|
| Synonyms: | CAH15_MOUSE | Ca15 | Car15 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35484.02 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_651955 |
|---|
| Residue: | 324 |
|---|
| Sequence: | MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
|
|
|
|---|
| BDBM10888 |
|---|
| n/a |
|---|
| Name | BDBM10888 |
|---|
| Synonyms: | 1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 | SPR_2 | US10172837, Zonisamide | Zonisamide | Zonisamide (ZNA) | Zonisamide (ZNS) | Zonisamide, 1 | Zonisamide, ZNS |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H8N2O3S |
|---|
| Mol. Mass. | 212.226 |
|---|
| SMILES | NS(=O)(=O)Cc1noc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
