| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
|---|
| Ligand | BDBM50300203 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_592893 (CHEMBL1048396) |
|---|
| Ki | 7860±n/a nM |
|---|
| Citation |  Temperini, C; Innocenti, A; Scozzafava, A; Parkkila, S; Supuran, CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem53:850-4 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 13 |
|---|
| Name: | Carbonic anhydrase 13 |
|---|
| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29445.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8N1Q1 |
|---|
| Residue: | 262 |
|---|
| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
|
|
|
|---|
| BDBM50300203 |
|---|
| n/a |
|---|
| Name | BDBM50300203 |
|---|
| Synonyms: | (S)-6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one | 6-(1S-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one | CHEMBL572366 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18O4 |
|---|
| Mol. Mass. | 262.301 |
|---|
| SMILES | COc1cc2oc(=O)ccc2cc1[C@@H](O)CC(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
