| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 15 |
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| Ligand | BDBM50300204 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_592895 (CHEMBL1048398) |
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| Ki | 461±n/a nM |
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| Citation |  Temperini, C; Innocenti, A; Scozzafava, A; Parkkila, S; Supuran, CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem53:850-4 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 15 |
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| Name: | Carbonic anhydrase 15 |
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| Synonyms: | CAH15_MOUSE | Ca15 | Car15 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35484.02 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_651955 |
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| Residue: | 324 |
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| Sequence: | MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
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| BDBM50300204 |
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| n/a |
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| Name | BDBM50300204 |
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| Synonyms: | (2R)-2-acetylamino-N-benzyl-3-methoxypropanamide | (R)-2-Acetylamino-N-benzyl-3-methoxy-propionamide | (R)-2-acetamido-N-benzyl-3-methoxypropanamide | (R)-N-benzyl 2-acetamido-3-methoxypropionamide | (R)-N-benzyl 2-acetamido-3-methoxypropionamide, | CHEMBL58323 | Erlosamide | LACOSAMIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C13H18N2O3 |
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| Mol. Mass. | 250.2936 |
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| SMILES | COC[C@@H](NC(C)=O)C(=O)NCc1ccccc1 |r| |
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| Structure | 
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