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TargetTranscription factor HES-1
LigandBDBM50378457
Substrate/Competitorn/a
Meas. Tech.ChEMBL_598858
IC50 7800±n/a nM
Citation Arai MAMasada AOhtsuka TKageyama RIshibashi M The first Hes1 dimer inhibitors from natural products. Bioorg Med Chem Lett 19:5778-81 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Transcription factor HES-1
Name:Transcription factor HES-1
Synonyms:Hairy and enhancer of split 1
Type:PROTEIN
Mol. Mass.:29762.25
Organism:Mus musculus
Description:ChEMBL_598858
Residue:282
Sequence:
MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL
ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE
VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQAHPALQAPPPPPPSGPAGPQHA
PFAPPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAF
AHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTSDSMWRPWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50378457
n/a
NameBDBM50378457
Synonyms:CHEMBL572017
TypeSmall organic molecule
Emp. Form.C24H28O13
Mol. Mass.524.4713
SMILESC\C=C1\[C@H]2OC=C([C@H]1CC(=O)OC[C@@H](OC[C@H]1O[C@@H](O2)[C@H](O)[C@@H](O)[C@@H]1O)c1ccc(O)c(O)c1)C(O)=O |r,c:5|
Structure
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