| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor HES-1 |
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| Ligand | BDBM50378459 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598858 (CHEMBL1044690) |
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| IC50 | 9600±n/a nM |
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| Citation |  Arai, MA; Masada, A; Ohtsuka, T; Kageyama, R; Ishibashi, M The first Hes1 dimer inhibitors from natural products. Bioorg Med Chem Lett19:5778-81 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcription factor HES-1 |
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| Name: | Transcription factor HES-1 |
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| Synonyms: | HES1_MOUSE | Hairy and enhancer of split 1 | Hes-1 | Hes1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29762.25 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_598858 |
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| Residue: | 282 |
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| Sequence: | MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL
ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE
VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQAHPALQAPPPPPPSGPAGPQHA
PFAPPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAF
AHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTSDSMWRPWRN
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| BDBM50378459 |
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| n/a |
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| Name | BDBM50378459 |
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| Synonyms: | NUDIPOSIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C27H36O12 |
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| Mol. Mass. | 552.5675 |
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| SMILES | COc1cc2C[C@H](CO)[C@@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](c3cc(OC)c(O)c(OC)c3)c2c(OC)c1O |r| |
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| Structure | 
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