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TargetTranscription factor HES-1
LigandBDBM50378459
Substrate/Competitorn/a
Meas. Tech.ChEMBL_598858
IC50 9600±n/a nM
Citation Arai MAMasada AOhtsuka TKageyama RIshibashi M The first Hes1 dimer inhibitors from natural products. Bioorg Med Chem Lett 19:5778-81 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Transcription factor HES-1
Name:Transcription factor HES-1
Synonyms:Hairy and enhancer of split 1
Type:PROTEIN
Mol. Mass.:29762.25
Organism:Mus musculus
Description:ChEMBL_598858
Residue:282
Sequence:
MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL
ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE
VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQAHPALQAPPPPPPSGPAGPQHA
PFAPPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAF
AHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTSDSMWRPWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50378459
n/a
NameBDBM50378459
Synonyms:NUDIPOSIDE
TypeSmall organic molecule
Emp. Form.C27H36O12
Mol. Mass.552.5675
SMILESCOc1cc2C[C@H](CO)[C@@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](c3cc(OC)c(O)c(OC)c3)c2c(OC)c1O |r|
Structure
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